Olena Stasyk
PhD in Biological Sciences, Associate Professor. Senior Researcher at MCCAP
Olena Stasyk studied at the Department of Genetics and Biotechnology, Faculty of Biology, Ivan Franko State University of Lviv, from 1992 to 1997.
In 2008, she defended her PhD dissertation entitled “Identification of Novel Genes Involved in Catabolite Regulation in the Methylotrophic Yeast Hansenula polymorpha” in the specialty 03.00.11 – Cytology, Cell Biology, and Histology.
Professional Experience
1998–2005 – Engineer, First-Class Engineer, and Leading Engineer at the Department of Molecular Genetics and Biotechnology, Institute of Cell Biology of the National Academy of Sciences of Ukraine (ICB NAS of Ukraine);
Since 2006 – Leading Engineer at the Department of Cell Signaling Mechanisms, ICB NAS of Ukraine;
2008–2025 – Junior Researcher at the Department of Cell Signaling Mechanisms, ICB NAS of Ukraine;
2010–2025 – Associate Professor at the Department of Biochemistry, Faculty of Biology, Ivan Franko National University of Lviv;
Since 2025 – Senior Researcher at the Microbial Culture Collection of Antibiotic Producers and, concurrently, Associate Professor at the Department of Genetics and Biotechnology, Ivan Franko National University of Lviv.
Individual Grants
2006 – Grant of the President of Ukraine for Gifted Youth for the project “Development of Domestic Genetically Engineered Yeast Producers of Medical Proteins (Human Insulin and Hepatitis B Vaccine)”.
2006 – FEMS Research Fellowship 2006-1: “Evaluation of the Physiological Roles of Transporter-like Glucose Sensors in the Methylotrophic Yeast Hansenula polymorpha and Human Pathogen Candida albicans.”
Collaborative Research Projects
2015–2019 – Research team member of the project “Modeling Molecular Processes Characteristic of Parkinson’s Disease in Yeast Cells and Analysis of the Effects of Exogenous and Endogenous Factors on Aggregation and Degradation of Human α-Synuclein” within the targeted interdisciplinary research program of the National Academy of Sciences of Ukraine “Molecular and Cellular Biotechnologies for Medicine, Industry, and Agriculture”.
2017–2019 – Principal Investigator of the state-funded research project Bh-48F “Investigation of the Mechanisms of Small-Molecule-Induced Autophagic Degradation of Aberrant Forms of Human α-Synuclein in Model Biosystems.”
2020–2022 – Research team member of Grant No. 872146 – RESBIOS – H2020-SwafS-2018-2020/H2020-SwafS-2019-1 “RESponsible Research and Innovation Grounding Practices in BIOSciences” (Horizon 2020).
Research Interests
Her principal research interests include:
- Catabolite regulation of methylotrophic metabolism;
- Mechanisms of peroxisome biogenesis and degradation in non-conventional yeasts;
- Development of novel Parkinson’s disease models based on eukaryotic microorganisms and human neuronal cell lines.
Selected Publications
- Demash DV, Stasyk OG, Vaskiv OV, Shuvaieva HYu, Tupychak MA, Vovk OI, Hromyko OM, Prokopiv AI, Stasyk OV. Method for Obtaining an Extract of the Leguminous Plant Indigofera spicata with Antimicrobial and Antitumor Properties. Utility Model Patent No. 160018, Ukraine, 2025.
- Stasyk OG, Stasyk OV. Production of Recombinant Proteins in the Methylotrophic Yeasts. In: Biotechnology of Yeasts and Filamentous Fungi. Springer International Publishing, 2024; 1–25.
- Nagalievska MR, Sabadashka MV, Stasyk OG, Sybirna NO. Open Science and Public Engagement for the Dissemination of Achievements of Life Sciences: Lessons Learned from Ivan Franko National University of Lviv. Studia Biologica. 2022;16(4):69–86.
- Nishtuk YV, Stasyk OV, Stasyk OG. Spermidine Activates Autophagy but Does Not Rescue Human Neuroblastoma SH-SY5Y Cells from the Effects of Arginine Starvation. Studia Biologica. 2022;16(3):35–48.
- Hrushanyk NV, Stasyk OV, Stasyk OG. Oxidative Stress Regulation in the Yeast Ogataea polymorpha Producer of Human α-Synuclein. The Ukrainian Biochemical Journal. 2020;92(5):120–133.
- Stasyk OG, Stasyk OV. Glucose Sensing and Regulation in Yeasts. In: Non-conventional Yeasts: From Basic Research to Application. Springer International Publishing, 2019; 477–519.
- Stasyk OG et al. Glucose Regulation in the Methylotrophic Yeast Hansenula (Ogataea) polymorpha Is Mediated by a Putative Transceptor Gcr1. International Journal of Biochemistry & Cell Biology. 2018;103:25–34.
- Farré JC et al. A New Yeast Peroxin, Pex36, a Functional Homolog of Mammalian PEX16, Functions in the ER-to-Peroxisome Traffic of Peroxisomal Membrane Proteins. Journal of Molecular Biology. 2017;429(23):3743–3762.
- Petryk N et al. Functional Study of the Hap4-like Genes Suggests that the Key Regulators of Carbon Metabolism HAP4 and Oxidative Stress Response YAP1 in Yeast Diverged from a Common Ancestor. PLoS ONE. 2014;9(12).
- Stasyk OG et al. Identification of Hexose Transporter-like Sensor HXS1 and Functional Hexose Transporter HXT1 in the Methylotrophic Yeast Hansenula polymorpha. Eukaryotic Cell. 2008;7(4):735–746.
Textbooks and Teaching Materials
- Protein Chemistry: Textbook approved by the Ministry of Education and Science of Ukraine. Edited by N.O. Sybirna. Lviv: Ivan Franko National University of Lviv, 2010. 393 p.
- Methodological Guidelines for Independent Study in Biochemistry, Bioorganic Chemistry, Radiobiology, and Molecular Biology. Lviv: Ivan Franko National University of Lviv, 2013. 116 p.
- Comprehensive Biochemistry Practicum: Construction and Analysis of Hansenula polymorpha Methylotrophic Yeast Strains Capable of Producing Heterologous Proteins. Educational and methodological manual. Lviv: Ivan Franko National University of Lviv, 2016. 104 p.
- Comprehensive Biochemistry Practicum: Enzymatic Methods of Analysis. Part I. Educational manual for laboratory classes. Lviv: Ivan Franko National University of Lviv, 2018. 72 p.
- Comprehensive Biochemistry Practicum: Enzymatic Methods of Analysis. Part II. Educational manual for laboratory classes. Lviv: Ivan Franko National University of Lviv, 2019. 84 p.
Sorption-Luminescence Method for Determination of Dipicolinic Acid
Vasylechko V., Bagday S., Shevchuk L., Voloshinovskii A., Gryshchouk G., Gromyko O., Kalychak Ya.
IEEE 15th International Conference “Nanomaterials: Applications & Properties” (IEEE NAP-2025). Bratislava, Slovakia, Sep. 7-12
Metabolic engineering of Streptomyces explomaris for increased production of the reverse antibiotic nybomycin
Shu, W., Stegmüller, J., Rodriguez-Estevez, M., Rückert-Reed, C., Kalinowski, J., Gromyko, O., Rebets, Y., Luzhetskyy, A., Wittmann, C.
Microb Cell Fact. 24, 227 (2025)
Potential of compost-derived actinomycetes for low-density polyethylene degradation
Szczyrba, E., Pokynbroda, T., Gąszczak, A., Koretska, N., Tistechok, S., Roman, I., & Gromyko, O.
Polymers. 17(17), 2318 (2025)
Genome analysis and characterization of Enterococcus sp. SB12 isolated from Carpathian artisanal cheese
Mushynska, V., Tistechok, S., Roman, I., Slyvka I., Tsisaryk O., Gromyko O., Shtapenko O., Syrvatka V.
Current Microbiology. 82, 349 (2025)
Effect of physico-chemical modification of clinoptilolite composites on their antimicrobial activity
Vasylechko V., Sydorchuk V., Manko N., Kostiv O., Klyuchivska O., Ilkov O., Bagday S., Zelinskiy A., Gromyko O., Stoika R., Kalychak Y.
Chemistry & Chemical Technology. 19 (2), 183–195 (2025)
Site‑specific community structure and plant growth‑promoting properties of cultured actinomycetes associated with Deschampsia antarctica from Galindez Island, Antarctica
Roman I., Khylchuk O., Fedorenko V., Gromyko O.
Folia Microbiologica, (2025)
Identification and heterologous expression of an NRPS biosynthetic gene cluster responsible for the production of the pyrazinones Ichizinone A, B and C
Oberhäuser P., Myronovskyi M., Stierhof M., Gromyko O. and Luzhetskyy A.
Microbial Cell Factories, 24. 131 (2025)
Gromomycins: An unprecedented class of triterpene antibiotics produced by a novel biosynthetic pathway
Tistechok S., Bratiichuk D., Sucipto H., Gummerlich N., Stierhof M., Gromyko O., Fries F., Fedorenko V., Müller R., Zapp J., Myronovskyi M., Luzhetskyy A.
Angewandte Chemie International Edition, 64(22), e202422270 (2025)
Mumia qirimensis nov. isolated from the rhizosphere of Phyllostachys viridiglaucescens (Carrière) Riviere & C. Rivier
Kachor A., Roman I., Fedorenko V., Gromyko O.
International Journal of Systematic and Evolutionary Microbiology 75(3), 006737 (2025)
Description of Streptomyces explomaris nov., isolated from the coastal soil rhizosphere of Juniperus excelsaand reclassification of Streptomyces libani as a later heterotypic synonym of Streptomyces nigrescens
Shu W., Rückert-Reed C., Gromyko O., Tistechok S., Kalinowski J., Luzhetskyy A. and Wittmann C.
International Journal of Systematic and Evolutionary Microbiology 75(5), 006711 (2025)
Complete genome sequence of Mumia sp. Pv 4-285 isolated from the rhizosphere of Phyllostachys viridiglaucescens (Carrière) Rivière & C. Rivière
Kachor A. , Samborskyy M., Rebets Y., Gromyko O.
Microbiology Resource Announcement 14(1), e00822-24 (2025)
Genomic analysis of an Antarctic actinomycete Micrononospora endolithica strain AA-459
Роман І.І., Громико О.М.
Вісн. Укр. тов-ва генетиків і селекціонерів 22 (1–2), 24-28 (2024)
Antibacterial action of novel zeolite-based compositions depends upon doping with Ag(+) and Сu(2+) cations
Manko N.O., Ilkov O.O., Klyuchivska O.Yu., Vasylechko V.O., Sydorchuk V.V., Kovalska N.P., Kostiv O.I., Bagday S.R., Zelinskiy A.V., Gromyko O.M., Skrypchenko N.V., Kalychak Yа.M., Stoika R.S.
Ukr.Biochem.J 96(5). 104-118 (2024)
https://doi.org/10.15407/ubj96.05.104
Фітостимулювальні властивості актиноміцетів ризосфери Phyllostachys vi-ridiglaucescens
Качор А. І., Тістечок С. І., Федоренко В. О., Громико О. М.
Фактори експериментальної еволюції організмів 35, 93-98 (2024)
Phylogenomic analyses of the genus Actinoplanes: description of four novel genera
Roman, I., Fedorenko, V., Gromyko, O.
Int J Syst Evol Microbiol 74(7). 006464 (2024)
Study of antibacterial effect of transcarpathian clinoptilolite compositions modified in different chemical ways
Manko N., Vasylechko , Kostiv O., Klyuchivska O., Sydorchuk V., Ilkov O., Bagday S., Zelinskiy A., Gromyko O., Kalychak Y., Stoika R.
Studia Biologica 18(2). 3-19 (2024)
Genome sequence of Umezawaea sp. strain Da 62-37 isolated from the rhizosphere of Deschampsia antarctica E.Desv. (Galindez Island, maritime Antarctic)
Roman I., Tistechok S., Gromyko O.
Microbiology Resource Announcement. 13(4). e0001924 (2024)
Draft genome sequence of Enterococcus sp. SB12 isolated from artisanal cheese of the Carpathian
Mushynska V., Roman I., Tistechok S., Slyvka I., Tsisaryk O., Gromyko O., Shtapenko O., Syrvatka V.
Microbiology Resource Announcement 13(1) (2024)
Evaluetion of antimicrobial activity and in vivo wound healing properties of copper nanoparticles and copper nanoparticles nanoemulsion
Shtapenko O., Syrvatka V., Horbay R., Dzen Y., Slyvchuk O., Gromyko O., Gevkan I.
Biointerface Research in Applied Chemistry 14(1), 15 (2024)
Bacterial community and culturable actinomycetes of Phyllostachys viridiglaucescensAntonie van Leeuwenhoek
Kachor, A., Tistechok, S., Rebets, Y., Fedorenko V., Gromyko O.
Antonie van Leeuwenhoek 117, 9 (2024)
Властивості актиноміцетів ризосфери Colabantus quitensis (Kunth) Bartl. (о. Бут, Морська Антарктика)
Роман І.І., Парнікоза І.Ю., Сираватка В.Я., Федоренко В.О., Громико О.М.
Фактори експериментальної еволюції організмів 33, 152-157 (2023)
Plant growth promoting properties of an antarctic strain Amycolatopsis sp. Cq 72-27
Roman I., Gromyko O.
Ukrainian Antarctic Journal 21(1), 79–89 (2023)
Diversity and Bioactive potential of Actinomycetia from the rhizosphere soil of Juniperus excelsa
Tistechok S., Roman I., Fedorenko V., Luzhetskyy A., Gromyko O.
Folia Microbiologica 68, 645–653 (2023)
Штам актиноміцетів Streptomyces sp. Je 1-93, Продуцент Антифунгальних Антибіотиків
Тістечок С., Федоренко В., Громико О.
Вісник Львівського університету. Серія біологічна 88, 17-25 (2023)
Scandium-microorganism in new biotechnologies
Syrvatka V., Rabets A., Gromyko O., Luzhetskyy A., Fedorenko V.
Trends in biotechnology 40 (9), 1088-1101 (2022)
Flavacol and its novel derivative 3-β-hydroxy flavacol from Streptomyces sp. Pv 4-95 after the expression of heterologous AdpA
Tistechok S., Stierhof M., Kachor A., Myronovskyi M., Gromyko O., Luzhetskyy, A.
Microorganisms 10(12), 2335
Doi: 10.3390/microorganisms10122335
Furaquinocins K and L: Novel Naphthoquinone-Based Meroterpenoids from Streptomyces sp. Je 1-369
Tistechok S., Stierhof M., Myronovskyi, M., Zapp J., Gromyko, O., Luzhetskyy, A.
Antibiotics 11(11), 1587
Doi: 10.3390/antibiotics11111587
Synthesis of the novel cage amides and imides and evaluation of their antibacterial and antifungal activity
Palchykov , Gaponov A., Manko N., Finiuk N., Novikevych O., Gromyko O., Stoika R. Pokhodylo N.
Ukr. Biochem. J. 94 (3), 68-80 (2022)
Screening of Thiopeptide-Producing Streptomycetes Isolated From the Rhizosphere Soil of Juniperus excelsa
Tistechok, S., Myronovskyi, M., Fedorenko, V., Luzhetskyy, A., Gromyko, O.
Curr Microbiol 79(10), 305 (2022)
The diversity and antibacterial activity of culturable actinobacteria isolated from the rhizosphere soil of Deschampsia antarctica (Galindez Island, Maritime Antarctic)
Tistechok, S., Skvortsova, M., Mytsyk, Yu., Fedorenko, V., Parnikoza, I., Luzhetskyy, A., Gromyko, O.
Polar Biol 44, 1859–1868 (2021)
https://doi.org/10.1007/s00300-021-02924-2
New kendomycin derivative isolated from Streptomyces sp. Cl 58-27
Paulus С., Gromyko O., Luzhetskyy A.
Molecules 26(22), 6834 (2021)
Isolation and characterization of culturable actinobacteria associated with Polytrichum strictum (Galindez Island, the maritime Antarctic)
Gromyko O., Tistechok, S., Roman, I., Aravitska, O., Luzhetskyy, A., Parnikoza, I., Fedorenko, V.
Ukrainian Antarctic Journal 2, 82-97 (2021)
Synthesis properties of silver nanoparticles-antibiotic conjugates for study of antibiotic-resistance mechanisms
Syrvatka V., Karachkovska A., Gromyko O., Kulyk N., Fedorenko V.
Optical Engineering 60(3), 037101 (2021)
Genetic identification and antimicrobial activity of Streptomyces strain Je 1–6 isolated from rhizosphere soil of Juniperus excelsa Bieb.
Tistechok S.I., Tymchuk I.V., Korniychuk O.P., Fedorenko V.O., Luzhetskyy A.M., Gromyko O.M.
Cytology and Genetics, 55(1), 28-35 (2021)
A novel solid-phase extraction method for preconcentration of silver and antimicrobial properties of the Na-cliniptelolite-Ag composite
Vasylechko V., Fedorenko V., Gromyko O., Gryshchouk G., Kalychak Ya. , Tistechok S., Us I., Tupys A.
Materials Today: Proceedings 35(4), 548-551 (2021)
https://doi.org/10.1016/j.matpr.2019.10.049
Screening of Thiopeptide-Producing Streptomycetes Isolated From the Rhizosphere Soil of Juniperus excelsa
Tistechok S., Myronovskyi M., Fedorenko V., Luzhetskyy A., Gromyko O.
Current microbiology 79, 305
Doi: 10.1007/s00284-022-03004-2
Honeybee chitosan-melanin complex: Isolation and investigation of antimicrobial activity
Manko N., Gromyko O., Tistechok S., Lutsyk M.Jr., Stoika R.
Ukrainian Biochemical Journal 92(6), 143-153 (2020)
https://doi.org/10.15407/ubj92.06.143
Sorption Preconcentration of Silver for Atomic Absorption Analysisand Antibacterial Properties of the Acid-modified Clinoptilolite – Ag
Vasylechko V.O., Fedorenko V.O., Gromyko O.M., Gryshchouk G.V., Kalychak Y.M., Tistechok S.I., Us I.L.,Tupys A.
Methods and objects of chemical analysis 15 (2), 73-82 (2020)
https://doi.org/10.17721/moca.2020.73-82
Antagonistic and plant growth promoting properties of actinomycetes from rhizosphere Deschampsia antarctica E. Desv. (Galindez island, Antarctica)
Tistechok S., Skvortsova M., Luzhetskyy A, Fedorenko V., Parnikoza I., Gromyko O.
Ukrainian Antarctic Journal 1(18), 169-177 (2019)
https://doi.org/10.33275/1727-7485.1(18).2019.140
Біосинтетичний потеціал актиноміцетів ризосфери Helianthemum stevenii Rupr. Ex Juz. & Pozd
Тістечок С., Мицик Ю., Федоренко В., Громико О.
Innov Biosynt Bioeng 3 (2), 105-113 (2019)
https://doi.org/10.20535/ibb.2019.3.2.170129
Design, development and application of whole-cell based antibiotic-specific biosensor
Rebets Y., Schmelz S., Gromyko O, Tistechok S., Petzkee L., Scrima A., Luzhetskyy A.
Metabolic Engineering 47, 263–270 (2018)
https://doi.org/10.1016/j.ymben.2018.03.019
Solid phase extractive preconcentration of silver from aqueous samples and antimicrobial properties of the clinoptilolite-Ag composite
Vasylechko V., Fedorenko V., Gromyko O., Gryshchouk G., Kalychak M., Zaporozhets O., Lototska M.
Adsorption Science & Technology 35(7-8), 602-611 (2017)
https://doi.org/10.1177/0263617417703509
Розроблення умов глибинного біосинтезу антибіотика ландоміциу А
Тодосійчук Т.С., Федоренко В.О., Молочко М.В., Громико О.М.
Наукові вісті НТУУ "КПІ" 3, 82-88 (2017)
https://doi.org/10.20535/1810-0546.2017.3.96444
Screening of actinomycetes – potential biocontrol agents of the typical trees infections
Tistechok S., Fedorenko V., Gromyko O.
Visnyk of L’viv Univ. Biology Series, 75, 119-126 (2017)
http://dx.doi.org/10.30970/vlubs.2017.75
Стрептоміцети ризосферної зони осоки шорстко волосистої (Carex hirta L.) та їх антагоністичні властивості при нафтовому забрудненні грунту
Буньо Л., Громико О., Цвілинюк О., Терек О., Федоренко В.
Вісник Львівського ун-ту. Серія біологічна 69, С. 163-173 (2015)
Отримання високоактивних стрептоміцин-резистентних продуцентів бактеріолізинів Streptomyces albus.
Громико, О. М., Буцяк, А. В., Федоренко, В. О., & Тодосійчук, Т. С.
Technology Audit and Production Reserves 2(4(22), 44–50 (2015)
https://doi.org/10.15587/2312-8372.2015.40552
Albaflavenol B, a new sesquiterpene isolated from the terrestrial actinomycete, Streptomyces sp.
Raju R., Gromyko O., Fedorenko V., Luzhetskyy A., Muller R.
J. of Antibiotics 68(4), 286 – 288 (2015)
https://doi.org/10.1038/ja.2014.138
Oleamycins A and B: new antibacterial cyclic hexadepsipeptides isolated from a terrestrial Streptomyces sp.
Raju R., Gromyko O., Butsiak A., Fedorenko V., Luzhetskyy A., Muller R.
J. of Antibiotics 67, 339-343 (2014)
https://doi.org/10.1038/ja.2014.1
Антагоністичні властивості актиноміцетів, виділених із ризосфери чистотілу великого Chelidonium majus L.
Громико О.
Вісник Львівського ун-ту. Серія біологічна 64, 279-286 (2014)
Oleaceran: A Novel Spiro[isobenzofuran-1,2′-naptho[1,8-bc]furan] Isolated from a Terrestrial Streptomyces sp.
Raju R., Gromyko O., Fedorenko V., Luzhetskyy A., Muller R.
Organic Letters 15(14), 3487-3489 (2013)
https://doi.org/10.1021/ol401490u
Lorneic acids C and D, new trialkyl-substituted aromatic acids isolated from a terrestrial Streptomyces sp.
Raju R., Gromyko O., Fedorenko V., Luzhetskyy A., Muller R.
J. of Antibiotics 66, 347-349 (2013)
https://doi.org/10.1038/ja.2013.18
Rubimycinone A, a new anthraquinone from a terrestrial Streptomyces sp.
Raju R., Gromyko O., Fedorenko V., Herrmann J., Luzhetskyy A., Muller R.
Tetrahedron Letters 54(8), 900–902 (2013)
https://doi.org/10.1016/j.tetlet.2012.11.130
Pimprinols A–C, from the terrestrial actinomycete, Streptomyces sp.
Raju R., Gromyko O., Fedorenko V., Luzhetskyy A., Muller R.
Tetrahedron Letters 53(24), 3009–3011 (2012)
https://doi.org/10.1016/j.tetlet.2012.03.134
Juniperolide A: A New Polyketide Isolated from a Terrestrial Actinomycete Streptomyces sp.
Raju R., Gromyko O., Fedorenko V., Luzhetskyy A., Plaza A., Muller R.
Organic Letters, 14(23), 5860–5863
https://doi.org/10.1021/ol302766z
Leopolic acid A, isolated from a terrestrial actinomycete Streptomyces sp.
Raju R., Gromyko O., Fedorenko V., Luzhetskyy A., Muller R.
Tetrahedron Letters 53(46), 6300–6301 (2012)
https://doi.org/10.1016/j.tetlet.2012.09.046
Антагоністичні властивості актиноміцетів прикореневої зони маслини європейської Olea europaea L.
Громико О.
Вісник Львівського ун-ту. Серія біологічна 59, 209-215 (2012)
Вплив N-метил-N`-нітро-N-нітрозогуанідину та N-мелил-N-нітрозометил-сечовини на антибіотичну активність продуцента сіоміцину Streptomyces sioyaensis Lv 81
Грубський Я., Аравіцька О., Мироновський М., Громико О., Осташ Б., Федоренко В.
Мікробіологія і біотехнологія 2, 28-35 (2009)
https://doi.org/10.18524/2307-4663.2009.2(6).102417Отримання та генетична трансформація протопластів штаму Streptomyces nogalater IMET 43360
Аравіцька О. Климишин Д., Громико О., Федоренко В.
Вісник Львів. ун-ту. Сер. біол. 48, 69-74 (2008)
Використання міжродової кон’югації Escherichia coli-Streptomyces для перенесення рекомбінантних ДНК в штам Streptomyces nogalater IMET 43360
Климишин Д.О., Громико О.М.,Федоренко В.О.
Cytology and Genetics 41(5), 3-8 (2007)
Мутанти Streptomyces nogalater IMET43360 з підвищеним рівнем синтезу протипухлинного антибіотика ногаламіцину
Громико О.М., Кириченко Н.В., Федоренко В.О.
Вісник Львів ун-ту. Сер. біол. 35, 121-127 (2004)
Generation of Streptomyces globisporus SMY622 strain with increased landomycin E production and it’s initial characterization
Gromyko O., Rebets Yu., Ostash B., Luzhetskyy A., Fukuhara M., Bechthold A., Nakamura T., Fedorenko V.
J. of Antibiotics 57(6), 383-389 (2004)
https://doi.org/10.7164/antibiotics.57.383
Generation of new landomycins by combinatorial biosynthetic manipulation of the lndGT4 gene of the landomycin E cluster in S. globisporus
Ostash, U. Rix, L. Remsing-Rix, T.Liu, F. Lombo, A. Luzhetskyy, O. Gromyko, C. Wang, A. F. Brana, C. Mendez, J. A. Salas, V. Fedorenko, and J. Rohr
Chemistry and Biology 11, 547-555 (2004)
https://doi.org/10.1016/j.chembiol.2004.03.011
Розрахункова модель виробництва протипухлинного антибіотика “Ландоміцин Е”
Сидоров Ю.І., Федоренко В.О., Громико О.М., Новиков В.П., Влязло Р.Й., Верес Р.М.
Вісник НУ “Львівська політехніка”. Хімія, технологія речовин та їх застосування, 461, С.204-208 (2002)